The Effect of Ischemic Training on Exercise Endurance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Exercise duration before and after 12 weeks of training during a submaximal exercise test and distance walked on a 6-minute walk test.
研究概览
简要总结
The purpose of this study is to determine if reducing blood flow to an exercising muscle during exercise training will enhance the training effect on that muscle in people who have limited exercise because of congestive heart failure
详细描述
The objective of this study is to determine whether reduction of blood flow during stair-stepping and cycling ergometer leg exercise will contribute to an improvement in whole body exercise capacity or submaximal exercise endurance in patients with mild congestive heart failure. Two groups of 25 patients with mild to moderate CHF, aged 30-70, will be trained for 12 weeks. The experimental group will train with pressure cuffs inflated on one thigh and lower leg during exercise. The cuff will be applied on alternate legs during training, such that each leg has the same duration of ischemic training. The control group will train for a similar duration and intensity without pressure cuffs on the legs. Pre and post training measures will include VO2peak, exercise duration at 30% VO2peak, 6 minute walk test, Minnesota Living with Heart Failure questionnaire
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 30 Years 至 71 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mild Congestive Heart Failure
- •Must be able to exercise
排除标准
- •Venous or arterial thrombus
- •Lower extremity arthritis
- •Blood clotting abnormalities
- •Claudication
- •Peripheral vascular disease
- •Evidence of deep vein thrombosis on ultrasound
结局指标
主要结局
Exercise duration before and after 12 weeks of training during a submaximal exercise test and distance walked on a 6-minute walk test.
次要结局
- Peak cycle ergometer VO2max test before and after training