Resistive Exercise Versus HIIT on Calcium and Vitamin D

Not Applicable

• Conditions: Calcium; Premenopause; Vitamin D Deficiency
• Interventions: Other: resistive exercise; Other: high intensity interval training; Dietary Supplement: calcium and vitamin D

• Registration Number: NCT05795504
• Lead Sponsor: Cairo University

Brief Summary

A comparison between resistive exercise and high intensity interval trainig on calcium and vitamin d in premenopausal women.

Detailed Description

A total of 57% of women were vitamin D deficient with higher vitamin D deficiency found among premenopausal women (64.7%). Concentrations of 25(OH) D, defined as severely deficient (\< 12 ng/ml), deficient (12-19 ng/ml), insufficient (20-30 ng/ml) and sufficient (\> 30 ng/ml). Both severe vitamin D deficiency and calcium deficiency was significantly more frequent in premenopausal women compared to postmenopausal women. So, it is important to find effective therapeutic approaches to treat vitamin D deficiency among these women

Study Timeline

• Study Start: 2023-03-01
• Study First Submitted: 2023-03-21
• Study First Submitted QC: 2023-03-21
• Study First Posted: 2023-04-03
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-19
• Last Update Posted: 2024-08-20
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-15

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Premenopausal women having reduced calcium level (less than 500mg) intake as recorded by 24 hours' dietary recall method and vitamin D deficiency (12-19 ng/ml).
• Their ages will range from 40 to 45 years.
• Their BMI will range from 25-30 kg/m2.
• Don't receive hormonal replacement therapy.

Exclusion Criteria

• Smoking.
• History of chronic disease (uncontrolled hypertension, diabetes mellitus)
• Osteoporosis.
• severe musculoskeletal disorders
• cardiovascular disease, thyroid dysfunction

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
resistive exercises	calcium and vitamin D	Premenopausal women in group A will perform resistive exercise for upper and lower limbs, three times per week in addition to calcium and vitamin d supplementations.
high intensity interval training	calcium and vitamin D	Premenopausal women in group B will receive high intensity interval training for three times per week in addition to calcium and vitamin D supplementations
resistive exercises	resistive exercise	Premenopausal women in group A will perform resistive exercise for upper and lower limbs, three times per week in addition to calcium and vitamin d supplementations.
high intensity interval training	high intensity interval training	Premenopausal women in group B will receive high intensity interval training for three times per week in addition to calcium and vitamin D supplementations
conventional therapy	calcium and vitamin D	Premenopausal women in group C will receive calcium and vitamin D supplementations only.

Primary Outcome Measures

Name	Time	Method
Vitamin D serum level	three months	a blood sample of each participant will be taken to measure serum vitamin D level before and after the study
serum calcium level	three months	a blood sample will be taken from each participant to measure calcium level of each participant before and after the study.

Trial Locations

Locations (1)

Faculty of physical therapy; 🇪🇬 Giza, Egypt