Minor Troponin Elevations in Patients With Atrial Fibrillation

Completed

• Conditions: Atrial Fibrillation; Myocardial Ischemia
• Interventions: Diagnostic Test: No intervention

• Registration Number: NCT03683836
• Lead Sponsor: University of Turku

Brief Summary

This study aims at identifying the etiology of troponin-T elevations in patients with atrial fibrillation visiting the emergency department.

Detailed Description

The aim of this study is to identify the factors associated with minor cardiac troponin-T elevations in patients presenting in emergency department (ED) with atrial fibrillation (AF) diagnosis , and the possible implications it has on the patients prognosis. Data on 3394 patients from the Turku university hospital catchment area with diagnosis of AF on admission to ED and minor troponin-T elevation were analyzed. Patients were classified into three groups according to the troponin-T value: troponin \<15ng/l, 15-50ng/l and 51-100ng/l. Individual patient records were reviewed.

Study Timeline

• Study Start: 2016-06-01
• Study First Submitted: 2018-09-22
• Study First Submitted QC: 2018-09-22
• Study First Posted: 2018-09-25
• Primary Completion: 2023-10-30
• Study Completion: 2023-10-30
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3394

Inclusion Criteria

• two troponin T tests within 72 hours of ED admission
• Prior diagnosis of AF or AF at admission

Exclusion Criteria

• Age < 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Study Group	No intervention	-

Primary Outcome Measures

Name	Time	Method
All-cause mortality, myocardial infarction, ischemic stroke	12 months	Major adverse cardiac or cerebrovascular event within one year