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Clinical Trials/NCT01364103
NCT01364103
Completed
Not Applicable

Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

Seoul National University Hospital1 site in 1 country33 target enrollmentFebruary 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Responsiveness
Sponsor
Seoul National University Hospital
Enrollment
33
Locations
1
Primary Endpoint
stoke volume index
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.

Registry
clinicaltrials.gov
Start Date
February 2011
End Date
May 2011
Last Updated
14 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jin-Tae Kim

assistant professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

  • neurosurgery under general anesthesia
  • \< 8 years old

Exclusion Criteria

  • cardiac disease
  • pulmonary, renal and hepatic disease
  • infectious disease
  • hematologic and muscular disease

Outcomes

Primary Outcomes

stoke volume index

Time Frame: before and after volume loading (20 minutes)

Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion

Study Sites (1)

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