Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

Not Applicable

Completed

• Conditions: Fluid Responsiveness

• Registration Number: NCT01364103
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02
• Primary Completion: 2011-05
• Study Completion: 2011-05
• Study First Submitted: 2011-05-24
• Study First Submitted QC: 2011-05-31
• Study First Posted: 2011-06-02
• Status Verified: 2012-01
• Last Update Submitted: 2012-01-31
• Last Update Posted: 2012-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• neurosurgery under general anesthesia
• < 8 years old

Exclusion Criteria

• cardiac disease
• pulmonary, renal and hepatic disease
• infectious disease
• hematologic and muscular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
stoke volume index	before and after volume loading (20 minutes)	Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion

Trial Locations

Locations (1)

Seoul national university hospital; 🇰🇷 Seoul, Korea, Republic of