To study the efficacy of Zinc bio fortified wheat based food in improving low Zinc status in Indian school childre
- Registration Number
- CTRI/2015/06/005913
- Lead Sponsor
- ETH Eidgenossische Technische Hochschule Zurich
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 270
zinc deficient otherwise healthy Indian school children
1. Severe anemia (Hb < 7 g/dl).
2. Consumption of a supplement or dietary supplement containing Zn.
3. Use of drugs that affect the metabolism of Zn, including reducing absorption or increasing excretion; for example tuberculosis medications (ethambutal and isoniazides), drugs used as treatment for entamoeba hystolica (diiodohydroxyquin), drugs that reduce stomach acidity (H2 blockers and proton pump inhibitory), antidepressants (nialamide and isocarboxazid), anti-inflammatory drugs (corticosteroids), diuretics (thiazides), aspirin, penicillamine and alcohol.
4. Suffering from a chronic disease affecting the metabolism of Zn, such as kidney disease or chronic gastrointestinal problems, as for example enter colitis, ulcers and other diseases disturbing the absorption of micro nutrients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma zinc status, C reactive proteins, alpha 1- acid glycoprotein,Timepoint: Baseline <br/ ><br>Mid point ( 1- 5 months) <br/ ><br>endline(6 months) <br/ ><br>Followup (8 months)
- Secondary Outcome Measures
Name Time Method Hemoglobin, plasma ferritinTimepoint: Baseline <br/ ><br>Mid point ( 1- 5 months) <br/ ><br>endline(6 months) <br/ ><br>Followup (8 months)