Treatment of Severe Male Infertility - Predictive Factors (Imaging)
- Conditions
- Male Infertility
- Interventions
- Diagnostic Test: MRI
- Registration Number
- NCT02931721
- Lead Sponsor
- Turku University Hospital
- Brief Summary
Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).
- Detailed Description
Sperm recovery rate in non-obstructive azoospermia (NOA) men is 43% in Turku University Hospital, depending on the diagnosis leading to NOA. To date, there are no known parameters known to differentiate between successful and unsuccessful sperm recovery.
MRI is performed on men prior to the operation, and the objective is to compare the functional parameters assessed by magnetic resonance imaging between the group of men with positive and the men with negative sperm recovery in testicular microdissection sperm extraction (MD-TESE).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 30
- non obstructive azospermia
- malignancy
- contraindication for fertility treatment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description MRI Positive MRI Men with sperm found in MD-TESE Control group MRI No intervention, fertile MRI Negative MRI Men with no sperm found in MD-TESE
- Primary Outcome Measures
Name Time Method Functional difference in testicular MRI depending on MD-TESE outcome (=sperm recovery) Baseline/ pre-invention ADC differences by diagnosis and outcome
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Turku University Hospital, Dept of Obst and Gyn
🇫🇮Turku, Finland
Dept of Obst and Gyn
🇫🇮Turku, Finland