The prevalence of parasympathetic dysfunction in dialytic patients attending Lampang hospital hemodialysis unit for maintenance hemodialysis

Not Applicable

Completed

• Conditions: End- stage renal diseaseHemodialysisParasympathetic dysfunction; Parasympathetic dysfunction; hemodialysis; heart rate variation

• Registration Number: TCTR20190826007
• Lead Sponsor: ampang hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-01-01
• Study Start: 2019-08-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

- End-stage renal disease required long-term hemodialysis
- Dialysis vintage more than 12 weeks
- Dialysis sessions at least 2 sessions per week

Exclusion Criteria

- Cirrhosis
- Heart failure NYHA class III-IV
- Arrhythmia: atrial fibrillation, atrial flutter, sinus node dysfunction, atrioventricular block
- Hypo/hyperthyroidism
- Epilepsy
- Parkinson's disease
- Active cancer
- Previously kidney transplantation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of parasympathetic dysfunction Pre hemodialysis Heart rate variability during deep breathing

Secondary Outcome Measures

Name	Time	Method
Predictors of parasympathetic dysfunction At baseline Age, sex, DM, dialysis vintage, antihypertensive drugs, serum phosphate, serum albumin