Down's Syndrome Patients Behavior Correlations to Periodontal Disease Status
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Global behavior - observation and scoring based on a behavior scale
研究概览
简要总结
This study aimed at correlating global behavior of Down's Syndrome patients to periodontal disease status.
详细描述
There is a higher prevalence and severity of periodontal disease in Down's Syndrome patients. Plaque levels in these patients are high due to poor hygiene habits. Behavior also may contribute to the overall periodontal condition.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 15 Years 至 52 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Down's Syndrome Diagnose characterized by the whole chromosomal aneuploidy 15 to 52 years
- •Absence of severe hearing loss could impair the comprehension about the dental treatment
- •Absence of severe visual loss that could impair the comprehension about the dental treatment
- •Presence of at least four teeth being one for hemiarch.
- •Diagnose of gingivitis and periodontitis
- •Absence of acute periodontal disease and necrotizing periodontal disease.
排除标准
- •Use of alcohol
- •Menopause
- •Pregnancy
- •Absence of all teeth
- •Uncontrolled diabetes mellitus
- •Uncontrolled hyperthyroidism
- •Uncontrolled hypertension
- •Coagulopathy
- •Use of illicit drugs
- •Head and neck radiotherapy
- •Chemotherapy
- •Non-cooperative patients or patients with other diseases as autism.
结局指标
主要结局
Global behavior - observation and scoring based on a behavior scale
时间窗: One day
Behavioral aspects: Interaction to evaluator, Communicative intention, Attention time, Response to conversation, Comprehension of concrete/no concrete situations with/without visual support, Parental interference, Acceptance of activities, Mimic, Eye contact, Participation in the dialogue (speech), Logical time sequence, Dialogue keeping, Word production Scores: 0 - absence, 1 - strictly presented, 2 - evidently presented.
Periodontal disease (gingivitis and periodontitis) measured by a periodontal probe and classified according to severity
时间窗: One day
Severe periodontitis was defined by the presence of ≥ 2 interproximal sites in different teeth with clinical attachment level (CAL) ≥ 6mm and ≥1 interproximal site with pocket probing depth (PPD) ≥5mm. Moderate periodontitis was defined by the presence of ≥ 2 interproximal sites in different teeth with CAL ≥ 4mm or ≥ 2 interproximal sites in different teeth with PPD ≥5mm. Mild periodontitis was defined as ≥ 2 interproximal sites in different teeth with ≥ 3 mm CAL and ≥ 2 interproximal sites in different teeth with ≥ 4 mm PPD or at least 1 site with PPD ≥ 5 mm (20,21). Gingivitis was determined as follows: Subjects were considered healthy if presented PPD ≤3mm/BOP extent scores \< 10% and with gingivitis if presented PPD ≤3mm/ bleeding on probing (BOP) extent scores \>10%. Prevalence of periodontal disease was the sum of gingivitis, mild, moderate and severe periodontitis.
次要结局
未报告次要终点
研究者
Carla Andreotti Damante
Associate professor
University of Sao Paulo