Frequency of Metabolic Syndrome in Down Syndrome Patients

Completed

• Conditions: Metabolic Syndrome X; Down Syndrome

• Registration Number: NCT00864461
• Lead Sponsor: Universidad de Guanajuato

Brief Summary

The aim of this study is to assess the frequency of metabolic syndrome in Down syndrome patients because the prevalence of diabetes mellitus and obesity is higher in individuals with Down syndrome than in the general population.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2009-03-17
• Study First Submitted QC: 2009-03-17
• Study First Posted: 2009-03-18
• Study Start: 2009-09-01
• Primary Completion: 2009-12-21
• Study Completion: 2010-03-31
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-02
• Last Update Posted: 2017-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

• Clinical diagnosis of Down syndrome

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Exclusion Criteria

• History of congenital cardiac defects requiring open-heart surgery
• History of gastroenterologic anomalies requiring bowel resection and/or ongoing medical intervention
• History of leukemia or other cancer
• History of hypothyroidism requiring thyroid hormone replacement

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To asses the frequency of the metabolic syndrome among Down syndrome patients. Metabolic syndrome was defined by Adult Treatment Panel III criteria modified by Halley-Castillo.	One year

Secondary Outcome Measures

Name	Time	Method
Evaluate the insulin resistance and insulin sensitivity using the HOMA and QUICKY methods.	One year

Trial Locations

Locations (1)

School of Medicine, University of Guanajuato; 🇲🇽 Leon, Guanajuato, Mexico