Study of Metabolic Syndrome in Patients Undergoing Endovascular Aortic Repair (EVAR)
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Metabolic Syndrome
- Sponsor
- University of Thessaly
- Enrollment
- 220
- Primary Endpoint
- Mortality
- Last Updated
- 5 years ago
Overview
Brief Summary
This prospective study aims to identify the prevalence of metabolic syndrome in patients undergoing EVAR and the implications of metabolic syndrome on the postoperative outcome, the major complications, the thromboembolic events and the perioperative mortality and morbidity of the patients undergoing vascular surgery.
Detailed Description
Patients scheduled for elective EVAR will be randomly divided in two groups. One group patients with metabolic syndrome and one without. Metabolic syndrome is defined by the definition of 2009 as: Increased waist circumflex (\>94 cm in men and \> 80 cm in women), increased triglycerides or in therapy, decreased HDL (\< 40 mg/dl in men and \<50mg/dl in women) or in therapy, Increased blood pressure (Systolic Blood Pressure\>130 mmHg or Diastolic Blood Pressure\>85 mmHg) or in therapy, increased fasting glucose (\>100mg/dl) or in therapy. All the patients will be monitored throughout the perioperative period, at 30 days, 6 and 12 months, and any major or minor complication will be recorded.
Investigators
Elena Arnaoutoglou
Professor of Anesthesiology
University of Thessaly
Eligibility Criteria
Inclusion Criteria
- •elective EVAR
Exclusion Criteria
- •Patients incapable to give informed consent
- •Pregnancy
- •Systematic Inflammatory disease
- •Use of steroids
- •Emergency surgery
- •Prior ICU admission
Outcomes
Primary Outcomes
Mortality
Time Frame: 12 months
Patients after EVAR who died in 12 months
Secondary Outcomes
- Systematic inflammatory response(12 months)
- Postimplantation syndrome(12 months)
- Renal insufficiency(12 months)
- Cardiovascular events(12 months)
- Thromboembolic events(12 months)
- Complications of surgical procedure(12 months)