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Clinical Trials/NCT00105573
NCT00105573
Completed
Not Applicable

Prevention for Infants of Low-Income Depressed Mothers

University of Rochester1 site in 1 country218 target enrollmentJanuary 2004
ConditionsDepression

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Depression
Sponsor
University of Rochester
Enrollment
218
Locations
1
Primary Endpoint
Maternal depression
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

This study will compare three interventions for depressed, low income mothers and determine which is most effective in treating maternal depression and in fostering development in infants.

Detailed Description

Poorly educated, low income mothers are at high risk for becoming depressed. The effects of living in poverty and being reared by a depressed parent can be detrimental to an infant's development. Effective interventions to reduce maternal depression and strengthen the mother-infant relationships are needed. Participants will be randomly assigned to one of three groups. Group 1 mothers will receive 16 weekly sessions of interpersonal psychotherapy (IP) designed to directly treat maternal depression. Group 1 participants will have monthly follow-up visits for 1 year. Participants in Group 2 will receive 16 weekly sessions of IP followed by 1 year of in-home, infant-parent psychotherapy, an intervention addressing relationship difficulties between depressed mothers and their infants. Group 3 mothers will be invited to attend informational meetings as well as be referred to local services available to people with depression. All mother-child pairs will be evaluated when the child is 12, 16, 24, and 36 months of age. Evaluations will involve questionnaires, diagnostic interviews, developmental assessments, and video- and audio-taped measures.

Registry
clinicaltrials.gov
Start Date
January 2004
End Date
April 2010
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sheree Toth

Executive Director, Mt. Hope Family Center, and Associate Professor

University of Rochester

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Maternal depression

Time Frame: Measured when the child is 12, 16, 24, 36, and 48 months of age

Child development

Time Frame: Measured when the child is 12, 16, 24, 36, and 48 months of age

Infant-parent attachment

Time Frame: Measured when the child is 12, 16, 24, 36, and 48 months of age

Study Sites (1)

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