Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Facial expression recognition test
研究概览
简要总结
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour...).
This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.
We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.
The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
详细描述
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.
Study progress (patients):
Inclusion visit :
Psychiatric evaluation Psychological evaluation
Ophthalmic visit
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age : >18 years
- •Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
- •Stability of treatment >1 month
- •Mini Mental State > 26
- •Affiliation to social security
- •Agreement of patients
排除标准
- •Patients with cognitive disorders, dementia, mental retardation...
- •Patients with serious neurological pathologies
- •Patients with a vision contrast altered.
- •Patients who do not understand the words associated with an emotion
- •Pregnant women
- •Person who participate to an other study
结局指标
主要结局
Facial expression recognition test
时间窗: % of exact responses
次要结局
- Lexical decision test(The time to respond)
