Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
- Conditions
- Gilles de la Tourette's Syndrome
- Interventions
- Behavioral: Facial expression recognition of emotion
- Registration Number
- NCT00664300
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Brief Summary
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour...).
This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.
We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.
The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
- Detailed Description
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.
Study progress (patients):
Inclusion visit :
Psychiatric evaluation Psychological evaluation
Ophthalmic visit
Protocol :
Facial expression recognition test Lexical decision test
Study progress (healthy volunteers):
Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Age : >18 years
- Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
- Stability of treatment >1 month
- Mini Mental State > 26
- Affiliation to social security
- Agreement of patients
- Patients with cognitive disorders, dementia, mental retardation...
- Patients with serious neurological pathologies
- Patients with a vision contrast altered.
- Patients who do not understand the words associated with an emotion
- Pregnant women
- Person who participate to an other study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 2 Facial expression recognition of emotion One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers
- Primary Outcome Measures
Name Time Method Facial expression recognition test % of exact responses
- Secondary Outcome Measures
Name Time Method Lexical decision test The time to respond
Trial Locations
- Locations (1)
CHU
🇫🇷Clermont-Ferrand, France