Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gilles de la Tourette's Syndrome
- Sponsor
- University Hospital, Clermont-Ferrand
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Facial expression recognition test
- Status
- Completed
- Last Updated
- 15 years ago
Overview
Brief Summary
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour...).
This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.
We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.
The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
Detailed Description
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers. Study progress (patients): Inclusion visit : Psychiatric evaluation Psychological evaluation Ophthalmic visit Protocol : Facial expression recognition test Lexical decision test Study progress (healthy volunteers): Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age : \>18 years
- •Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
- •Stability of treatment \>1 month
- •Mini Mental State \> 26
- •Affiliation to social security
- •Agreement of patients
Exclusion Criteria
- •Patients with cognitive disorders, dementia, mental retardation...
- •Patients with serious neurological pathologies
- •Patients with a vision contrast altered.
- •Patients who do not understand the words associated with an emotion
- •Pregnant women
- •Person who participate to an other study
Outcomes
Primary Outcomes
Facial expression recognition test
Time Frame: % of exact responses
Secondary Outcomes
- Lexical decision test(The time to respond)