跳至主要内容
临床试验/NCT00664300
NCT00664300已完成不适用

Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome

University Hospital, Clermont-Ferrand1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2007年8月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
1
主要终点
Facial expression recognition test

研究概览

简要总结

Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour...).

This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.

We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.

The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).

详细描述

20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.

Study progress (patients):

Inclusion visit :

Psychiatric evaluation Psychological evaluation

Ophthalmic visit

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age : >18 years
  • Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
  • Stability of treatment >1 month
  • Mini Mental State > 26
  • Affiliation to social security
  • Agreement of patients

排除标准

  • Patients with cognitive disorders, dementia, mental retardation...
  • Patients with serious neurological pathologies
  • Patients with a vision contrast altered.
  • Patients who do not understand the words associated with an emotion
  • Pregnant women
  • Person who participate to an other study

结局指标

主要结局

Facial expression recognition test

时间窗: % of exact responses

次要结局

  • Lexical decision test(The time to respond)

研究者

发起方
University Hospital, Clermont-Ferrand
申办方类型
Other

研究点 (1)

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