Study of Modified Constraint-Induced Aphasia Therapy Schedule to Treat Patients Following Sub-acute Stroke

Not Applicable

Completed

• Conditions: Aphasia
• Interventions: Other: Investigate efficacy of modified ciat schedule; Other: examine the efficacy of standard treatment versus modified ciat schedule

• Registration Number: NCT01625676
• Lead Sponsor: NRZ Magdeburg Median Kliniken GmbH & Co

Brief Summary

The purpose of this study is to assess the feasibility of modified Constraint-Induced Aphasia Therapy (CIAT) in the early sub-acute stage and to examine the efficacy of modified CIAT versus standard treatment with the same intensity of intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-08
• Primary Completion: 2010-10
• Study Completion: 2011-12
• Status Verified: 2012-06
• Study First Submitted: 2012-06-15
• Study First Submitted QC: 2012-06-19
• Last Update Submitted: 2012-06-19
• Study First Posted: 2012-06-21
• Last Update Posted: 2012-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• clinical diagnosis of first-ever stroke
• aphasia in sub-acute stage
• german speakers

Exclusion Criteria

• presence of residual aphasia
• dysarthria and apraxia of speech

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CIAT-Group	Investigate efficacy of modified ciat schedule	Patients received a modified constraint-induced therapy schedule
standard treatment group	examine the efficacy of standard treatment versus modified ciat schedule	patients received a standard aphasia therapy

Primary Outcome Measures

Name	Time	Method
Change of aphasia and aphasic syndromes by Aachen Aphasia Test (AAT)	pretreatment and 4 weeks
change from pretreatment in Aachen Aphasia Test at 8 weeks	pretreatment and 8 weeks
change from pretreatment in Aachen Aphasia Test at 1 year	pretreatment and 1 year

Secondary Outcome Measures

Name	Time	Method
Change of Communicative Activity (CAL)	pretreatment and 4 weeks
change from pretreatment in communication activity (CAL)at 8 weeks	pretreatment and 8 weeks
Change from pretreatment in communication activity (CAL)at 1 year	pretreatment and 1 year

Trial Locations

Locations (1)

NRZ Median Klinik; 🇩🇪 Magdeburg, Germany