The role of the cerebellum in reversal learning
- Conditions
- onderzoek bij gezonde vrijwilligersnot applicable
- Registration Number
- NL-OMON51434
- Lead Sponsor
- niversiteit Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 111
Healthy; Between 18 and 35 years of age; Righthanded; Nonsmoking; Normal or
corrected-to-normal vision; Willingness and ability to understand the nature
and content, to participate and to comply with the study requirements;
Willingness and ability to give written informed consent.
(1) Use of medication and drugs (except oral contraceptives); (2) Pregnancy or
possible pregnancy; (3) Head trauma or underwent brain surgery; (4)
Neurological or psychiatric condition; (5) Epilepsy or family history of
epilepsy; (6) Metal in the head (except for bridges behind the teeth); (7)
Heart problems; (8) Pacemaker or neurostimulator; (9) Medication pump; (10)
Electronic hearing device; (11) Consumption of more than 3 alcoholic beverages
a day; (12) Participation in a non-invasive brain stimulation study in the past
28 days; (13) Previous participation in 10 or more non-invasive brain
stimulation studies.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is reversal learning performance (e.g., how fast<br /><br>participants notice and implement a change in reward-punishment contingencies)<br /><br>as a function of cTBS condition during a computer task. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary study parameters are risk-taking as a function of cTBS condition<br /><br>during a computer task, and the moderating effects of state anger, state<br /><br>anxiety, trait aggression, trait impulsivity and vagally mediated HRV on<br /><br>risk-taking and reversal learning performance by cTBS condition.</p><br>