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Bupropion for the Treatment of Methamphetamine Dependence - 1

Phase 2
Completed
Conditions
Amphetamine-Related Disorders
Registration Number
NCT00069251
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Brief Summary

The purpose of this study is to assess the efficacy and safety of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence

Detailed Description

A double-blind, placebo-controlled, parallel-group design study in which 100 subjects will be randomly assigned to placebo or bupropion for 12 weeks with follow-up assessments 4 weeks following treatment. Adaptive randomization will be used to balance treatment groups based on gender.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Subject must have methamphetamine dependence as determined by the DSM-IV diagnosis
  • Subject must be willing to comply with study procedures.
  • Ability to verbalize understanding of consent form, provide written consent, and verbalize willingness to complete study procedures
  • Be able to comply with protocol requirements
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Exclusion Criteria
  • Please contact site for more information.
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Severity addiction
Methamphetamine use
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (5)

Matrix Institute on Addictions

🇺🇸

Costa Mesa, California, United States

South Bay Treatment Center

🇺🇸

San Diego, California, United States

Pacific Addiction Research Center

🇺🇸

Honolulu, Hawaii, United States

Powell Chemical Dependency Center

🇺🇸

Des Moines, Iowa, United States

University of Missouri - Kansas City

🇺🇸

Kansas City, Missouri, United States

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