NCT07042321招募中不适用
Triglyceride Glucol Index for Predicting the Value of No-Reflow in Patients Undergoing Emergency PCI for Acute Myocardial Infarction
The Third Xiangya Hospital of Central South University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2024年6月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The presence or absence of microvascular obstruction (MVO) diagnosed by cardiac magnetic resonance (CMR) within 3-7 days postoperatively
研究概览
简要总结
The goal of this prospective cohort study is to investigate the relationship between the TyG index and early identification of MVO in AMI patients undergoing emergency PCI and CMR imaging. The study will enroll approximately 300 AMI patients treated at Xiangya Third Hospital of Central South University from June 2024 to August 2025. The main questions it aims to answer are:
- How does the TyG index correlate with the early detection of MVO?
- What differences in cardiovascular adverse events during hospitalization exist between groups with varying TyG index levels? Participants will undergo emergency PCI and CMR imaging within 3-7 days post-procedure. Data collected will include demographic characteristics, clinical history, coronary angiography data, laboratory test indicators (especially metabolic markers such as blood glucose and lipids), IVUS-related plaque information, and CMR results.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years.
- •STEMI symptom onset time < 12 hours.
- •STEMI symptom onset time 12-48 hours, with ongoing ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias.
- •Very high-risk NSTEMI; undergoing emergency PCI treatment.
- •Voluntary signed informed consent form.
排除标准
- •Non-obstructive acute myocardial infarction.
- •Severe chronic kidney disease (defined as estimated glomerular filtration rate <20 mL/min per 1.73 m²).
- •Pregnant women or those planning to become pregnant.
- •Failure of emergency PCI.
- •Unclear CMR images
结局指标
主要结局
The presence or absence of microvascular obstruction (MVO) diagnosed by cardiac magnetic resonance (CMR) within 3-7 days postoperatively
时间窗: 3-7 days postoperatively
次要结局
未报告次要终点
研究者
Yu Cao
Cardiology Professor
The Third Xiangya Hospital of Central South University
研究点 (1)
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