Impact of Sarpogrelate in the Function of Endothelial Progenitor Cells

Not Applicable

• Conditions: Atherosclerosis

• Registration Number: NCT01548274
• Lead Sponsor: Aichi Gakuin University

Brief Summary

The purpose of this study is to evaluate the effects of Sarpogrelate in endothelial progenitor cells of patients with atherosclerosis.

Detailed Description

Endothelial progenitor cells play an important role in vasculogenesis and vascular repair. Sarpogrelate, a inhibitor of HT2A, is used an an anti-platelet drug, however, a direct effect in vascular cells is supposed.

Study Timeline

• Study Start: 2010-10
• Status Verified: 2012-03
• Study First Submitted: 2012-03-05
• Study First Submitted QC: 2012-03-05
• Last Update Submitted: 2012-03-05
• Study First Posted: 2012-03-08
• Last Update Posted: 2012-03-08
• Primary Completion: 2012-10
• Study Completion: 2012-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Patients with atherosclerosis

Exclusion Criteria

• Patients with high risk of bleeding
• Patients with pregnancy
• Patients with allergic reaction of Salpogrelate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
The number and function of endothelial progenitor cells	3 months

Trial Locations

Locations (1)

Aichi-Gakuin University; 🇯🇵 Nagoya, Aichi, Japan