CTRI/2025/09/094560尚未招募不适用
Retinal Thickness And White Cell Inflammatory Biomarkers In Diabetic Retinopathy - A Cross-Sectional Study
Depart Mahatma Gandhi Medical College and Research Institute1 个研究点 分布在 1 个国家目标入组 144 人开始时间: 2025年9月21日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 144
- 试验地点
- 1
- 主要终点
- 1. To estimate and compare the levels of white cell inflammatory biomarkers and retinal thickness among diabetics with and without retinopathy and in non-diabetic healthy controls.
研究概览
简要总结
There are few studies on retinal thickness and white blood cell inflammatory biomarker in diabetic retinopathy. The use of inflammatory biomarkers in diabetic retinopathy are also not much in use. If the use of inflammatory parameters for Diabetic Retinopathy is found to be effective and predictors, it will help in giving an early treatment and plan.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40.00 Year(s) 至 95.00 Year(s)（—）
- 性别
- All
入选标准
- •All willing patients with type 2 diabetes mellitus and willing to undergo OCT.
- •Age and gender match healthy individuals and willing to undergo OCT.
排除标准
- •Patients with conditions which alter the WBC markers [auto immune or inflammatory disorders such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, malignancies (past or present), medications such as corticosteroids, immunosuppressant or anti-inflammatory medication and hematological disorder such as anemia, leukemias and platelet disorders].
- •Patients with recent history of intraocular surgeries or ocular trauma (within 3 months).
- •Patients with ocular and systemic diseases affecting retinal thickness like (hypertension, glaucoma, optic neuritis, high myopia).
- •Media opacities preventing OCT imaging (corneal opacity, corneal edema, cataract, vitreous hemorrhage).
结局指标
主要结局
1. To estimate and compare the levels of white cell inflammatory biomarkers and retinal thickness among diabetics with and without retinopathy and in non-diabetic healthy controls.
时间窗: This is a one time study. There is no follow up
次要结局
未报告次要终点
研究者
Mohammed Raihan
Department Of Ophthalmology, Mahatma Gandhi Medical College and Research Institute
研究点 (1)
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