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临床试验/CTRI/2026/02/103848
CTRI/2026/02/103848招募中不适用

Effect of combined aerobic and resistance training on autonomic functions and exercise capacity in individuals with familial risk of hypertension

Centre for Physiotherapy and Rehabilitation Sciences1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2026年2月26日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
44
试验地点
1
主要终点
•Cardiac autonomic function

研究概览

简要总结

This prospective pre-test–post-test study will evaluate the effect of combined aerobic and resistance training on cardiac autonomic function and exercise capacity in normotensive young adults (18–30 years) with a familial history of hypertension. Forty-four participants will be recruited and allocated into an experimental group or control group. The intervention group will perform supervised combined exercise training (aerobic treadmill walking and resistance exercises) three times per week for four weeks. The intensity of intervention will range from 50-70% of 1RM progressing up to 60-80% of 1RM for resistance training and 50-60% of HRR progressing up to 60-70% of HRR for aerobic training. The control group will continue usual activities. Baseline data including cardiac autonomic recovery (heart rate variability), exercise capacity (6-minute walk test), and heart rate recovery, blood pressure, physical activity will be collected one day before the intervention, and post-intervention measurements will be taken one day after completion of 12 sessions of training using standardized protocols.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 30.00 Year(s)(—)
性别
All

入选标准

  • Individuals with systolic (SBP) and diastolic blood pressure (DBP) lower than 140/90 mmHg.
  • Individuals must have a father and/or a mother diagnosed with hypertension.
  • Individuals must be non-smokers.
  • Individuals in the normal range of body mass index (BMI) (18.5-24.9 kg/m2).
  • Subjects with low physical activity level, as defined by the International Physical Activity Questionnaire (IPAQ) classification.

排除标准

  • Individuals who are already diagnosed with hypertension, diabetes or other chronic disorders.
  • Individuals with any acute illness.
  • Individuals with musculoskeletal limitations to physical exercise.
  • Individuals with a history of chest pain and/or breathlessness.
  • Individuals who are current smokers and/ or have a history of alcohol consumption.

结局指标

主要结局

•Cardiac autonomic function

时间窗: At baseline (before the start of intervention) | Post intervention (after 12 sessions)

•Exercise capacity

时间窗: At baseline (before the start of intervention) | Post intervention (after 12 sessions)

次要结局

  • •Heart rate recovery(•Blood pressure)

研究者

发起方
Centre for Physiotherapy and Rehabilitation Sciences
申办方类型
Other [Jamia Millia Islamia,New Delhi-110025]
责任方
Principal Investigator
主要研究者

Adila Parveen

Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia

研究点 (1)

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