The influence of ramosetron on the analgesic effect of tramadol after laparoscopic gynecologic surgery: prospective, randomized, controlled trial
Not Applicable
Completed
- Conditions
- Not Applicable
- Registration Number
- KCT0001750
- Lead Sponsor
- CC Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 110
Inclusion Criteria
we enrolled 110 female patients between 19 and 65 years of age with an American Society of Anesthesiologists (ASA) physical status of I or II, who were undergoing laparoscopic gynecologic surgery.
Exclusion Criteria
Patients who were unable to use the IV PCA device unassisted, had used other antiemetics or steroids in the 24 h prior to surgery, were on antidepressants, had a known allergy to tramadol or ramosetron, had epilepsy, alcoholism, obesity (body mass index > 35), severe renal or hepatic insufficiency, or severe cardiopulmonary disease, were excluded.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The group difference in cumulative dose of tramadol .
- Secondary Outcome Measures
Name Time Method pain score; incidence of nausea and vomiting;total rescue antiemetic drug use;patients’ satisfaction;frequency of side effects