The Effect of Applying Modified NUTRIC Scoring System to Evaluate the Nutrition Risk and Giving Different Types of Nutritional Support on Clinical Outcomes in Critically Ill Patients
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- In-hospital mortality
Study Overview
Brief Summary
Malnutrition is very common in critically ill patients. It is quite important to evaluate nutritional status precisely. Heyland et al firstly reported NUTRIC score including age, APACHE II score, SOFA score, number of commorbidities, days from hospital to ICU admission and IL-6. Because the IL-6 is not routinely checked at ICU. A modified NUTRIC score without IL-6 is more practical. Previous studies showed lower in-hospital mortality in higher nutritional risk patients with higher caloric intake compared with lower caloric intake. However, there is still controversial regarding the in-hospital mortality between full caloric feeding and permissive underfeeding in critically ill patients. Herein the investigators conduct a study to investigate what kinds of nutritional supplements will decrease in-hospital mortality in different nutritional risk patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 100 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Medical intensive care unit patients
- •age elder than 20 years old
- •Intubated with ventilator support patients
- •Predicted ICU stay longer than 72 hours
Exclusion Criteria
- •NPO patients
- •Contraindication for enteral feeding
- •Upper or lower GI bleeding patients
- •Feeding with gastrostomy or Jejunostomy patients
- •Metoclopramide related EPS or Torsades de pointes history
Arms & Interventions
Low Nutritional Risk
modified NUTRIC score < 5
Intervention: volume-based feeding (Dietary Supplement)
High Nutritional Risk
modified NUTRIC score ≥ 5
Intervention: Trophic feeding (Dietary Supplement)
High Nutritional Risk
modified NUTRIC score ≥ 5
Intervention: volume-based feeding (Dietary Supplement)
Low Nutritional Risk
modified NUTRIC score < 5
Intervention: Trophic feeding (Dietary Supplement)
Outcomes
Primary Outcomes
In-hospital mortality
Time Frame: 90 days
mortality or discharge
Secondary Outcomes
No secondary outcomes reported
Investigators
Wang, Chen-Yu
Director of Medical Intensive Care Unit
Taichung Veterans General Hospital