A randomized trial to compare the efficacy of dexamethasone and dexmedetomidine as adjuvants to 0.5% Ropivacaine in Adductor Canal Block for postoperative pain relief

Not Applicable

• Conditions: Health Condition 1: S833- Tear of articular cartilage of knee, current

• Registration Number: CTRI/2020/02/023505
• Lead Sponsor: Department of Anaesthesia and Intensive care Government Medical College and Hospital Chandigarh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Age between 18 to 60 years of either sex.

2. American Society of Anaesthesiologist (ASA) physical status I and II of either sex.

3. BMI 20 to 30 kg/m2

4. Patients scheduled for ACL reconstruction surgery.

Exclusion Criteria

1. Patientâ??s inability to understand VAS.

2. Patients with coagulopathy and bleeding disorders.

3. Pre-existing peripheral neuropathy.

4. Patients having history of substance abuse.

5. Pre-existing local infection at the site of block.

6. Pregnant and lactating women.

7.Contraindication to study drugs: Paracetamol, Diclofenac, Dexamethasone, Dexmedetomidine, Ropivacaine.

8. Patients having hemodynamic instability, hypotension, bradycardia, hepatic dysfunction.

9. Patients on regular chronic pain management drugs for the last three months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the time to first rescue analgesia in patients receiving ACB with dexamethasone and dexmedetomidine as adjuvants to 0.5% ropivacaine following ACL surgery.Timepoint: Immediately after the block then 5,10, 15 ,60 minutes followed by 2, 4, 6, 8,12 and at 24-hour interval

Secondary Outcome Measures

Name	Time	Method
Quadriceps StrengthTimepoint: 12- and 24-hours after administering the block.;Ramsay Sedation ScoreTimepoint: Immediately after block then 5, 10, 15, 60 minutes and followed by 2, 4, 6, 8, 12- and 24-hours interval.;Range of movement at knee jointTimepoint: 12- and 24-hours after administering the block.;Timed up and go testTimepoint: 24 hours postoperatively;Total analgesic consumption, nausea, vomiting or any other complaint along with sedation score, hemodynamic variables; BP, PR, RR, VAS at rest and on movementTimepoint: Immediately after block then 5,10, 15 ,60 minutes followed by 2, 4, 6, 8,12 and at 24-hour interval. <br/ ><br> <br/ ><br>