Comparing pain relieving potential of giving Dexamethasone or Dexmedetomidine or Ketamine when given with 0.375% Ropivacaine for ultrasound guided erector spinae block in spinal surgery for pain relief
Not Applicable
- Conditions
- Health Condition 1: M259- Joint disorder, unspecified
- Registration Number
- CTRI/2023/09/057570
- Lead Sponsor
- Institute of Neurosciences Kolkata
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Aged 18–65 years
ASA grade I, II
Either gender
BMI < 24 kg/m2
Surgical procedure: spinal instrumentation surgeries involving the dorso-lumbar spine (D10-S1)
Duration of surgery: up to 4 hours
Exclusion Criteria
Patient refusal
ASA Grade III/ IV
Surgeries:
Scoliosis correction surgery
Spinal instrumentation surgery planned under intraoperative neuro-monitoring
Revision spine surgery
Duration of surgery >4 hours,
Patients with hypersensitivity to any of the drugs in use
History of congestive heart failure/ valvular heart disease/ IHD/ cardiac conduction block/ renal dysfunction/ hepatic disease/ pulmonary disease/ neuropsychiatric disorders/ coagulation abnormality
Puncture site infection
History of chronic pain or central neuropathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of duration of analgesia using VAS pain scoreTimepoint: 0 hr <br/ ><br>2 hr <br/ ><br>4 hr <br/ ><br>8 hr <br/ ><br>12 hr <br/ ><br>24 hr
- Secondary Outcome Measures
Name Time Method First request of rescue analgesicTimepoint: Anytime in first 24 hr;Intraoperative haemodynamic stabilityTimepoint: 10 min <br/ ><br>20 min <br/ ><br>30 min <br/ ><br>1 hr <br/ ><br>1.5 hr <br/ ><br>2 hr <br/ ><br>2.5 hr <br/ ><br>3 hr <br/ ><br>3.5 hr <br/ ><br>4 hr;Occurrence of PONV in postoperative periodTimepoint: Anytime in first 24 hr;Total intraoperative and postoperative opioid consumptionTimepoint: 24 hr