Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
- Conditions
- Acute CholecystitisCholecystectomy
- Registration Number
- NCT01548339
- Lead Sponsor
- University of Lausanne Hospitals
- Brief Summary
The purpose of this study is to compare the clinical outcomes of early versus delayed laparoscopic cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
- Detailed Description
In acute biliary cholecystitis, there was a dogma that patients should be operated within 72 hours of evolution. However, retrospective studies suggested that laparoscopic cholecystectomy even after 72 hours was safe. Moreover, some randomized controlled-trials did not found any differences in term of complications between early and delayed cholecystectomy, however none of these studies did separate patients according to the onset of symptoms. The aim of our present study was to compare the clinical outcomes of immediate versus delayed cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 86
- proven echographic cholecystitis
- pregnancy
- immunosuppression
- severe sepsis
- perforated cholecystitis
- peritonitis
- cholangitis
- acute pancreatitis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Number of Participants With Adverse Event ("Global Morbidity"). 30 postoperative days any adverse event occurring from time of diagnosis until the 30th postoperative day
- Secondary Outcome Measures
Name Time Method Postoperative Complications 30 postoperative days postoperative complications graded according to Clavien classification
Length of Stay 30 postoperative days total in hospital stay
Trial Locations
- Locations (1)
University of Lausanne Hospitals
🇨🇭Lausanne, Vaud, Switzerland
University of Lausanne Hospitals🇨🇭Lausanne, Vaud, Switzerland