Early Laparoscopic Cholecystectomy Versus Percutaneous Cholecystostomy Followed by Delayed Laparoscopic Cholecystectomy in Patients With Grade II Acute Cholecystitis According to Tokyo Guidelines
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 220
- 试验地点
- 2
- 主要终点
- operative difficulties as conversion, operative time, biliary injury
研究概览
简要总结
The aim of this study is to compare between early laparoscopic cholecystectomy versus percutaneous cholecystostomy followed by delayed interval laparoscopic cholecystectomy as regards the operative and postoperative complications
详细描述
A-Study setting: Department of Surgery, main university hospital, Faculty of Medicine, Alexandria University, Egypt. The study was approved by the Ethics Committee of our institution.
B-Study design: Retrospective clinical trial C-Study subjects: The target population are patients with preoperative diagnosis of grade II acute cholecystitis Those patients were subjected to surgery either early laparoscopic cholecystectomy or delayed laparoscopic cholecystectomy after percutaneous cholecystostomy
Inclusion criteria of the study patients:
-Specific written informed consent approved by our Institution's Ethics Committee was obtained from all the treated patients.
Exclusion criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with one of the criteria stated by grade II (moderate) Tokyo guidelines for acute cholecystitis who were managed either by early LC or by a bridging PC followed by delayed LC.
排除标准
- •grade I or III acute cholecystitis
- •common bile duct stones or jaundice,
- •Liver cirrhosis,
- •severe upper abdominal adhesions,
- •acalculous cholecystitis
- •major comorbidities in which laparoscopic surgery is contraindicated.
- •those who followed a conservative treatment for acute cholecystitis
结局指标
主要结局
operative difficulties as conversion, operative time, biliary injury
时间窗: at the time of cholecysctomy
as assessed by the main surgeon
postoperative complications
时间窗: 30 days after the operation
as assessed by clavien dindo classification
次要结局
未报告次要终点