Modern MR-Diagnostics of upper Extremity related Nerve injuries

Not Applicable

• Conditions: S54; S44; Injury of nerves at forearm level; Injury of nerves at shoulder and upper arm level

• Registration Number: DRKS00011545
• Lead Sponsor: BG Klinik Ludwigshafen, Klinik für Hand-, Plastische und Rekonstruktive Chirurgie - Schwerbrandverletztenzentrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-03
• Study Completion: 2023-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

acute traumatic nerve lesion (<72 hours) or iatrogenic nerve lesions of the upper extremity: radial, median and ulnar nerve distal to the brachial plexus and proximal of the wrist.
Nerve compression syndroms include, sulcus nervi ulnaris syndrome, loge de guyon syndrom,

patients male or female 18-99 years old, german or english speaking, able to reason, written consent

Exclusion Criteria

* Patient does not want to be included into the study or no written consent
* patient does not appear to follow up appointments
* not able to reason or not able to be included in the study
* inclusion in other studies evaluating medical drugs or medical devices
* absolute contra indications to MRI scans or implants that are not compatible with MRI (ICD, pace maker, many heart valves, brain or spinal cord stimulators or most other electric stimulators, insulin or other drug pumps, some ventriculoperitoneal shunts (VP shunts), cochlea implants, metal implants or foreign bodies located in soft tissue (located for example in eyes, abdomen, thorax), adiposities that prevents MRI scans,

in case of relative MRI contra indications only after informed and consent and approval of the radiologist: claustrophobia, joint replacements, tattoos, pricings, vessel stents, heart vessel stents, contraceptive coil,

life-threatening co-morbidities,

polytrauma
no German or English language skills
pregnancy
current immunosuppressive or antineoplastic therapy
strong psychiatric disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of intraoperative diagnosed nerve damage and diagnosis of the MR-Neurography

Secondary Outcome Measures

Name	Time	Method
Correlation of the fractional anisotropy as a numerical value from the MR-Neurography with the intraoperative diagnosis, electric nerve studies (surface skin nerve conduction study from a trained neurologist) and clinical examination