MR imaging for the detection and evaluation of periodontal diseases

• Conditions: K05.3; K05.2; Chronic periodontitis; Acute periodontitis

• Registration Number: DRKS00020761
• Lead Sponsor: Klinikum rechts der Isar, Abteilung für Diagnostische und Interventionelle Neuroradiologie, TU München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-04-06
• Study Start: 2020-04-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

Included were both, male and female patients with diagnosed, periodontitis as well as healthy control subjects (in the context of sequence optimization and as a healthy comparison collective). Diagnosis of generalized periodontitis was made when clinical periodontal attachment loss was present at >2 interdental sites at non-adjacent teeth and/or a probing pocket depth of >3mm at oral or lingual sites. At least 30% of teeth had to be affected by periodontitis. None of the healthy control subjects and the periodontitis patients received periodontal treatment within the past six month.

Exclusion Criteria

Patients with contraindications for an MRI examination (e.g. pacemaker, implanted defibrillator, artificial heart valves, cochlear implants, metal splinters, insulin pumps) were excluded. Further exclusion criteria were patients with pronounced claustrophobia, psychomotor agitation, pregnant as well as breastfeeding women and patients with a metastatic, malignant underlying disease.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Signal changes in MRI (signal-to-noise-ratio as well as volume of changes in mm3 - clinically determined parameters (bleeding on probing, pocket probing depth)

Secondary Outcome Measures

Name	Time	Method
bone resorption, attachment loss