14 Weeks Exercise Training on Lean Women With and Without PCOS
Not Applicable
Completed
- Conditions
- Polycystic Ovary Syndrome (PCOS)
- Interventions
- Other: 14 weeks exercise training
- Registration Number
- NCT02429128
- Lead Sponsor
- University of Copenhagen
- Brief Summary
The aim of this project is to investigate the pathophysiology of PCOS in regards to the metabolic profile including defects in insulin sensitivity in skeletal muscle and adipose tissue, and to investigate the effects of exercise training on these parameters.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 22
Inclusion Criteria
Women with PCOS
- Hyperandrogenism and/or hyperandrogenemia
- Regular menstruation
- Age: 20-40
- Inactive or low physical activity level
- Low to moderate fitness status
Inclusion Criteria: Women without PCOS
- Normal levels of plasma androgens
- Polycystic ovary and/or menstrual dysfunction
- Age: 20-40
- Inactive or low physical activity level
- Low to moderate fitness status
Exclusion Criteria
Women with and without PCOS
- Pregnancy or breast feeding
- Smoking
- Use of birth control pills 3 mo before enrolment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Lean PCOS training 14 weeks exercise training 14 weeks exercise training Lean healthy controls 14 weeks exercise training 14 weeks exercise training
- Primary Outcome Measures
Name Time Method Component of metabolic syndrome 14 weeks Peripheral insulin sensitivity measured by hyperinsulinemic euglycemic clamp methods.
Compliance to exercise training program as assessed by number of training sessions completed 14 weeks Superviced training program - no. of training sessions are noted by trainer. Compliance must be higher than 80%.
No change in Body Weight 14 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
August Krogh Building
🇩🇰Copenhagen, Østerbro, Denmark