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临床试验/CTRI/2019/06/019786
CTRI/2019/06/019786尚未招募2/3 期

A Comparative Clinical Study on the efficacy of Vaaluka Svedana followed by Kati-pristha-trikabasti with or without Erandamooladi Yogabasti in the management of Kati-Pristha-Trika Graha w.s.r. to Ankylosing Spondylitis.

All India Institute of Ayurveda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2019年7月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Reduction in pain

研究概览

简要总结

Ankylosing spondylitis (AS) is a systematic rheumatic disorder, which is characterized clinically by pain and stiffness of the back, and radiologically by arthritic changes in the sacroiliac joints and the entire spine. The chronic inflammation leads to progressive ossification of the spinal ligaments and facet joints.

Kati-Pristha-Trika Graha may be considered similar to Ankolysing Spondylitis in Ayurveda.Graha is one of the characteristic features of aggravated Vata Dosha.Moreover Kati,Prishtha and Trika are the places of Asthi Sandhi which again are the places for localisation of aggravated Vata Dosha.Graha/Stambha could be seen when Kaphavritta Vata condition develops.Hence in the treatment of Kati-Pristha-Trika Graha(Ankolysing Spondylitis), primary concernshould be effective treatment of Vata Dosha, which includes administration of Snehana, Svedana and Basti.

In this study,patients of ankylosing spondylitis will be taken according to inclusion criteria.Selected patients will be divided into two  groups by permuted block randomization.In first group ,vaaluka svedana followed by katipristhatrika basti with dhanwantharam thailam for 7 days each will be done followed by rasnasaptak kwath and simhanaad guggulun as follow up medications for 15 days.In second group,vaaluka svedana for 7 days will be done followed by katipristhabasti with dhanwantharan thailam for 7 days followed by yogabasti for 8 days.Follow up medications with Simhanaad Guggulu and Rasnasaptak Kwatha will be given for 15 days.In both groups,patients will be assessed as per assessment criteria.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1 Duration of the disease: 1yr to 10 years 2 Socio- economic status: All 3 Diagnosed cases of Ankylosing Spondylitis.

排除标准

  • 1 Chronicity of disease more than 10 yrs.
  • 2 Severely deformed joints.
  • 3 Cardiac disease, pulmonary tuberculosis, severe lung disease and pregnant women.
  • 4 Patients unfit for Snehana,Svedana and Basti Karma.

结局指标

主要结局

Reduction in pain

时间窗: 67 days

次要结局

  • Overall improvement in quality of life

研究者

申办方类型
Research institution and hospital

研究点 (1)

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