ACTRN12612001120864已完成3 期
Randomised controlled trial of early use of a simplified treatment regimen incorporating a half-dose, three-in-one blood pressure lowering pill vs. usual care for improving hypertension control
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 700
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •* The investigator is satisfied that the patient has persistent hypertension (SBP>140mmHg and/or DBP>90mmHg; or SBP>130mmHg and/or DBP>80mmHg in patients with diabetes mellitus or chronic kidney disease) requiring initiation of pharmacological treatment (in patients not taking drug therapy) or up-titration of pharmacological treatment (in patients taking single drug therapy)
- •*Trial Investigator is unsure as to whether a Triple Pill based therapy or usual care is better.
排除标准
- •*on 2 or more BP lowering drugs
- •* severe or uncontrolled hypertension (SBP > 180mmHg and/or DBP > 110 mmHg)
- •*Accelerated hypertension or hypertension at a level where the physician feels that slower up-titration of treatment is appropriate (e.g. elderly patients)
- •*Contraindication to any of the components of the Triple Pill
- •*Pregnancy, breast feeding, childbearing potential not on effective medically accepted method of child birth control.
- •*Unstable medical condition or known situation where medication regimen might be altered for a significant length of time, e.g. current acute cardiovascular event, planned coronary bypass graft operation, dialysis.
- •*Participants with clinically significant abnormal laboratory value judged to be unsuitable for trial participation by the investigator.
研究者
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