Effects of Repeated Memory Training on Memory Function and Addiction Related Processes

Not Applicable

Terminated

• Conditions: Substance-Related Disorders
• Interventions: Behavioral: Comparator memory training 1; Behavioral: Comparator memory training 2; Behavioral: Experimental memory training

• Registration Number: NCT03285256
• Lead Sponsor: Johns Hopkins University

Brief Summary

Prospective memory is the ability to implement an intention to the future (e.g. remember to take medication, attend a scheduled meeting), and has receive little attention in addiction. The investigators propose that prospective memory plays a critical, yet unrecognized, role in major human behavior change such as that required in addiction treatment. This study will determine the preliminary efficacy of prospective memory training in improving memory and executive functions while reducing illicit drug use in methadone patients. Participants will be randomly assigned to one of three conditions: an experimental memory training program or one of two comparator memory training programs.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-09-08
• Study First Submitted QC: 2017-09-12
• Study First Posted: 2017-09-15
• Study Start: 2018-05-01
• Primary Completion: 2019-10-01
• Study Completion: 2019-10-01
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-08
• Last Update Posted: 2020-01-10

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• Age 18-55; provision of written consent
• Enrolled in a substance use treatment program
• Sex with ≥ 2 partners in the last 30 days and sex without a condom on at least one occasion in the last year

Exclusion Criteria

• Severe psychiatric conditions associated with psychosis or any unstable psychiatric condition
• History of medical, psychiatric, or neurological conditions associated with significant cognitive impairment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Comparator Memory Training 1	Comparator memory training 1	Comparator memory training program
Comparator Memory Training 2	Comparator memory training 2	Alternative comparator memory training program
Experimental Memory Training	Experimental memory training	Experimental memory training program

Primary Outcome Measures

Name	Time	Method
Change in prospective memory over course of training	one month	Prospective memory will be evaluated within the program itself and measured as the percentage of correct responses within the program. Higher percentages are indicative of greater prospective memory performance.
Change in drug use and substance abuse over course of training.	one month	Drug use will be evaluated by urinalysis. Negative screens are indicative of drug abstinence.

Trial Locations

Locations (1)

Johns Hopkins University School of Medicine, Bayview Campus; 🇺🇸 Baltimore, Maryland, United States