DRKS00000446
Completed
Not Applicable
Effect of an automatic continuous positive airway pressure (APAP) ventilation therapy on exercise capacity in patients with congestive heart failure and obstructive sleep apnoea - APAP-Trial
Kardiologische Klinik, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum0 sites76 target enrollmentJune 29, 2010
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- I50.19
- Sponsor
- Kardiologische Klinik, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum
- Enrollment
- 76
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of congestive heart failure (CHF) obtained at least 12 weeks prior to inclusion
- •\- LVEF \= 45%
- •\- optimal CHF treatment according to recent guidelines provided by the German Cardiac Society (DGK)
- •\- Obstructive sleep apnoea (AHI \>\= 15/h) with \= 25% central events
- •\- routinely planned hospital admission for follow\-up visits (3 and 6 months)
- •\- stable medical heart failure therapy for at least 4 weeks prior to inclusion
- •\- willingness to participate in this study
- •\- written informed consent
Exclusion Criteria
- •\- implantation of a CRT\-D device or upgrading within the last 12 weeks
- •\- significant COPD (FEV1/VC \<70%)
- •\- respiratory insufficieny requiring long\-term oxygen therapy
- •\- daytime hypercapnia (pCO2 \>45mmHg)
- •\- ongoing APAP, BiPAP or ASV therapy
- •\- cardiothoracic surgery, PCI, myocardial infarction, transitory ischaemic attac or stroke within the last 12 weeks
- •\- untreated or therapy refractory restless\-legs syndrome
- •\- acute myocarditis within the last 3 months
- •\- pregnancy or breastfeeding women
- •\- complex sleep apnoea during APAP\-therapy initiation
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Impact of prophylactic continuous positive airway pressure in the delivery room (DR-CPAP) on neonates <1500g in a low-resource setting: A feasibility trialPaediatricsPACTR202208462613789Mbale Clinical Research Institute100
Completed
Not Applicable
The effect of Continuous Positive Airway Pressure (CPAP) on the collapsed lung during single-lung-ventilation in patients undergoing robot-assisted thoracoscopic esophageal resection: pulmonary complications, local and systemic cytokine productioEsophageal cancerCancerOesophagealISRCTN61458115niversity Medical Center Utrecht (UMCU), Department of Surgery (The Netherlands)30
Completed
Phase 4
Continuous Positive Airway Pressure (CPAP) use in men with obstructive sleep apnoea and erectile dysfunction.Obstructive Sleep ApnoeaErectile DysfunctionRespiratory - Sleep apnoeaReproductive Health and Childbirth - Other reproductive health and childbirth disordersACTRN12610000144011HMRC61
Completed
Not Applicable
Impact of standard continous positive airway pressure (CPAP) therapy on arterial hypertension in patients with obstructive sleep apnoea syndrome (OSAS)Obstructive sleep apnoeaNervous System DiseasesSleep disordersISRCTN42722501Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)40
Completed
Not Applicable
Effects of continuous positive airway pressure on cardiac autonomic control, airway inflammation and oxidative stress in Thai patients with obstructive sleep apneaObstructive sleep apneaAirway inflammationTCTR20160413001Faculty of Medicine, Khon Kaen University15