High Intensity Interval Training Versus Intermittent Fasting on Functional Capacity Among Overweight Subjects

Not Applicable

Completed

• Conditions: Overweight
• Interventions: Other: Intermittent Fasting 16/8 Protocol; Other: High Intensity Interval Training

• Registration Number: NCT04950062
• Lead Sponsor: Horus University

Brief Summary

The purpose of the study is to compare the effect of high-intensity interval training and intermittent fasting on improving body weight and functional capacity among overweight subjects.

Detailed Description

Exercise improves cardiorespiratory fitness, muscle strength, endurance, body composition, and decreases visceral fat. The, increase in physical activity and modification of eating behaviors are the first line of interventions given because of their low costs and low risks of complications.

Most commonly, the continuous exercise of moderate intensity, that has to be performed several days of the week to get target benefits have been used, on the other hand, different forms of training which aim to reduce time spent exercising by increasing exercise intensity have been considered as an alternative to increasing adherence to the training program which is supported by some researches that may have greater benefits as high intensity interval training improves the vascular function of the muscle capillary density and endothelial nitric oxide synthase(eNOS) levels. But there are some overweight people even some of the young people have restriction to perform exercise programs due to any medical problem that could interfere with exercise.

So, searching for optimal dietary interventions for obesity is still ongoing, but the modification in eating behaviors are hampered by difficulties in coping with a different diet. So, the diet with a fasting component that will be used in this study may be more effective than other complex and restrictive diets as it essentially limits the caloric intake to a specified period without major diet composition changes.

So, the aim of this study is to compare the effect of high-intensity interval training and intermittent fasting on improving body weight and functional capacity among overweight subjects.

Study Timeline

• Study Start: 2021-02-01
• Status Verified: 2021-06
• Study First Submitted: 2021-06-12
• Primary Completion: 2021-06-15
• Study Completion: 2021-06-30
• Study First Submitted QC: 2021-06-30
• Last Update Submitted: 2021-06-30
• Study First Posted: 2021-07-06
• Last Update Posted: 2021-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Subjects have to meet all the following criteria in order to participate in the study:

  1. Overweight subjects with age from 25 to 35 years.
  2. Body mass index will be range from 25 to 29.9 kg/m2.
  3. Waist circumference ≥ 80 cm2.
  4. A minimum of 70% of exercise program and diet regimen compliance will be required in order to be included.

Exclusion Criteria

• Subjects with the following disorders will be excluded from participating in this study:

  1. Musculoskeletal, cardiovascular disorders.
  2. Asthma, chronic obstructive pulmonary diseases.
  3. Any systemic disease or condition that might reduce adherence or tolerance to exercise or fasting.
  4. History of stroke.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intermittent fasting	Intermittent Fasting 16/8 Protocol	Group B that included 30 subjects will participate in intermittent fasting for 12 weeks, 3 times/week.
High intensity interval training	High Intensity Interval Training	Group A included 30 subjects who will participate in high intensity interval training on a treadmill for 12 weeks, 3 times/week.

Primary Outcome Measures

Name	Time	Method
Assessing the change in Vo2max	Baseline and 2 months post-intervention	Assessment via using Standard Bruce protocol will be used to measure (VO2) max. The Bruce protocol for multi stage treadmill testing of maximal exercise will be used. This will begin with stage 1 with walking slowly for three minutes at 2.7 Km/hr at a 10% grade (inclination), speed and grade then increased in every stage of 3 minutes and end at stage 7 or till exhaustion.
Assessing the change in body weight	Baseline and 2 months post-intervention	Assessment via using of body weight scale with height (m) scale to be able to calculate body weight (Kg).
Assessing the change in waist hip circumference	Baseline and 2 months post-intervention	Assessment via using Tape measures It will be used to measure waist and hip circumference and calculate waist hip ratio

Trial Locations

Locations (1)

Outpatient clinic - Faculty of Physical Therapy - Horus University; 🇪🇬 Damietta, Egypt