Evaluation of The Effect of Injectable Platelet-rich Fibrin With Collagen Membrane in Miller Class II Gingival Recession Coverage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Keratinized Tissue Thickness
研究概览
简要总结
This study aims to evaluate the effect of injectable Platelet-Rich Fibrin (i-PRF) in combination with collagen membrane in the treatment of Miller Class II gingival recession. Gingival recession is a common periodontal condition characterized by apical displacement of the gingival margin, which may lead to aesthetic concerns, root hypersensitivity, and increased risk of root caries.
The study will include patients diagnosed with Miller Class II gingival recession. Participants will be treated using a regenerative periodontal surgical approach involving coronally advanced flap combined with injectable platelet-rich fibrin and collagen membrane. Clinical parameters such as recession depth, clinical attachment level, and keratinized tissue width will be evaluated before and after treatment at specific follow-up intervals.
The objective is to compare the effectiveness of this combined regenerative approach in improving root coverage and soft tissue healing, and to assess its potential benefits in periodontal regeneration and esthetic outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both males and females of age ≥ 18
排除标准
- •History of systemic diseases (i.e. diabetes, autoimmune dysfunction, prolonged cortisone therapy, or chemotherapy) that contraindicated periodontal surgical treatment.
研究组 & 干预措施
Group 1
i-PRF +collagen membrane
干预措施: Group (1) (Procedure)
Group 2
CAF+SCTG
干预措施: Group 2 (Procedure)
结局指标
主要结局
Keratinized Tissue Thickness
时间窗: Baseline, 1 month ,3 months and 6 months after surgery
measured in millimeters (mm) using a endodontic file
次要结局
- Recession Depth (RD)(baseline,1 month,3 months,6 months after surgery)
- Recession Width (RW)(Baseline,1 month,3 months ,and 6 months after surgery)
- keratinized Tissue Height (KTH)(Baseline, 1 month, 3 months, 6 months after surgery)
- Probing Pocket Depth (PPD)(Baseline and 6 months after surgery)
研究者
Ahmed Ramadan Shawky Elsayed elazab
Teaaching Assistant, Faculty of Dentistry,Tanta University
Tanta University