A Comparative Study On Efficacy Of Injectable Platelet Rich Fibrin (i-PRF) And Platelet Rich Plasma (PRP) In Facial Scars - A Triple Blinded Randomized Clinical Trail.
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Anil Neerukonda Institute of Dental Sciences
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- surface area of the scar
Overview
Brief Summary
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Aim of this study is to compare the efficacy between Injectable Platelet-Rich Fibrin (i-PRF) and Platelet-Rich Plasma (PRP) in the treatment of Facial Scars. Patients who report with chief complaint of facial scar to the Department of Oral and Maxillofacial Surgery, Anil Neerukonda Institute of Dental Sciences, Visakhapatnam. Careful evaluation & selection of participants. Written Informed Consent will be taken from selected participants & Preoperative Patient and Observer Scar Assessment Scale (POSAS) will be takenrespectively. The co- investigator will be helping in blinding and allocation concealment. The participants will be randomly assigned to Group A & Group B. Both the Principal Investigator and Participant will be blinded. The Co-investigator will be helping with randomization, blinding and Allocation concealment. The Evaluator, who is blinded, will assess Postoperative outcomes one month after the last session in all the participants from both the groups by Patient and Observer Scar Assessment Scale (POSAS). The collected data will be consolidated and statistically analyzed.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant, Investigator and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 40.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Scars secondary to surgical incision and trauma.
- •Scars involving head and neck region.
- •Patients willing to participate in the study.
Exclusion Criteria
- •Scars secondary to burns, acne.
- •Scars that received any previous revision/treatment.
- •Patients with history keloid tendency, any active skin/systemic conditions, immunosuppression, bleeding and clotting disorders, pregnancy.
Outcomes
Primary Outcomes
surface area of the scar
Time Frame: 1 month
Secondary Outcomes
- pigmentation and texture(1 month)
Investigators
Narasimhadevara Santha Lakshmi Pratyusha
Anil Neerukonda Institute Of Dental Sciences