Blood Gas Comparison trial

Completed

• Conditions: Respiratory complaints

• Registration Number: NL-OMON27674
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 155

Inclusion Criteria

Patients (= 18 years) presenting in the ED with dyspoea, respiratory rate > 20/min or peripheral oxygen saturation <95%, a reliable saturation measured by pulse oximetry and an indication, determined by the treating physician, to determine the acid-bae, ventilation and oxygenation status by arterial blood gas.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Not capable to give informed consent within reasonable time after stabilisation and abating of the accompanying psychological stress, and no representative availabe to give informed consent on behalf of the patient.
- Arterial blood gas results are required for other reasons than determining the acid-base, ventilation and oxygenation status, such as determing the alveolar to arterial oxygen gradiënt (A-a gradient).
- No physician or qualified nurse available for ABG sampling.
- Failed ABG or VBG sampling after two attempts.
- Previous participation in the study.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main study endpoint is the frequency of alterations in treatment of patients with respiratory complaints in the emergency department (ED) based on venous blood gas (VBG) results compared to treatment based on arterial blood gas (ABG) results. We will assess which alterations in treatment occur, the characteristics of alterations and which ABG resuls cause the change.

Secondary Outcome Measures

Name	Time	Method
Secondary endpoints are the agreement between venous and arterial pH, bicarbonate, pCO2, lactate and pO2 and the correlation between venous and arterial pO2 and the peripheral oxygen saturation measured with pulse oximetry.