To study the effect of High Molecular Weight Hyaluronic Acid injection when given directly into Knee joint in patients with Osteoarthritis Knee
Not Applicable
Completed
- Conditions
- Health Condition 1: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2020/03/024224
- Lead Sponsor
- VMMC and Safdarjung hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 44
Inclusion Criteria
patients of either gender diagnosed with primary OA knee of tibiofemoral joint as defined by ACR cliniucal and radiographic criteria
Radiological grade II and III ofknee OA according to Kellgren-Lawrence classification
Body Mass Index <40
Exclusion Criteria
history of bleeding disorders
ipsilateral cruciate or collateral ligament injury
intra articular treatment with any product or joint lavage
any arthroscopic procedure within prior six months
any knee surgery within prior 12 months
any overlying skin infection
venous or lymphatic stasis
on anticoagulation therapy in previous 7 days
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the clinical outcome in OA knee following intra articular hyaluronic acid injection using VAS scoring system and KOOSTimepoint: 3 months after injection
- Secondary Outcome Measures
Name Time Method To assess the cartilage thickness pre and post hyaluronic acid injection by MRITimepoint: 3 months