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Clinical Trials/NCT03760939
NCT03760939
Terminated
Not Applicable

Clinical and Economical Evaluation of Colorectal Surgery in Ambulatory Care

IHU Strasbourg1 site in 1 country5 target enrollmentJanuary 3, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Surgery
Sponsor
IHU Strasbourg
Enrollment
5
Locations
1
Primary Endpoint
Mean cost evaluation
Status
Terminated
Last Updated
last year

Overview

Brief Summary

Enhanced recovery after surgery (ERAS) significantly decreases mortality, morbidity and hospital length of stay without increasing the rate of re-hospitalization. It reduces psychologic stress caused by surgery and decreases postoperative complications about 50 %, especially in colorectal surgery. ERAS is now the object of several Good Practices Recommendations and is about to become the reference strategy.

The development of ambulatory surgery is a French national concern. Its interest has been demonstrated in many surgical fields. It requires a reflection centered on the patient and a health care pathway organization involving all health care actors.

While hospitalization is still the standard practice for colonic surgery, the objective of this study is to evaluate the medical and economic impact of an ambulatory care for colorectal surgery.

Ambulatory care will be compared to standard hospitalization of patients who benefit from the ERAS program.

Detailed Description

Enhanced recovery after surgery (ERAS) significantly decreases mortality, morbidity and hospital length of stay without increasing the rate of re-hospitalization. It reduces psychologic stress caused by surgery and decreases postoperative complications about 50 %, especially in colorectal surgery. ERAS is now the object of several Good Practices Recommendations and is about to become the reference strategy. The development of ambulatory surgery is a French national concern. Its interest has been demonstrated in many surgical fields. It requires a reflection centered on the patient and a health care pathway organization involving all health care actors. Multiple interests have been shown: * Equivalent mortality and/or morbidity compared with standard hospitalizations * Medical and psychological benefits * Individualized and less invasive health care pathways, in favor of patient's autonomy * Multidisciplinary approach and innovative care * Heath care costs management (decrease of hospital length of stay, optimization of operating rooms). Ambulatory colectomies feasibility is recognized since 2013-2014 in France (Dr. Gignoux, MD in Lyon and Dr. Chasserant, MD in Le Havre). These ambulatory procedures are implemented in few expert centers with significant experience (more than 100 patients in Le Havre and more than 85 patients in Lyon) but several human and organizational limitations slow this innovative care. The risk of complications does not seem to be increased on condition of anticipate and provide a postoperative follow-up at home. While hospitalization is still the standard practice for colonic surgery, the objective of this study is to evaluate the medical and economic impact of an ambulatory care for colorectal surgery. Ambulatory care will be compared to standard hospitalization of patients who benefit from the ERAS program.

Registry
clinicaltrials.gov
Start Date
January 3, 2019
End Date
November 15, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
IHU Strasbourg
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or female over 18 years old
  • Patient able to understand the objectives and risks related to the trial
  • Patient able to give written informed consent
  • Patient able to understand and accept the health care program
  • Isolated colonic lesion located on the colon or the upper rectum
  • Any neoplastic or non-neoplastic colonic pathology
  • Colonic surgery except resection without continuity interruption (e.g. low cecum resection, partial colectomy, suture for polyp)
  • Moderate and/or controlled comorbidities
  • No history of multiple laparotomies
  • No psychosocial distress

Exclusion Criteria

  • Patient in exclusion period of another clinical study
  • Emergency surgical procedure
  • Type 1 diabetes
  • Presence of an uncontrolled preoperative anemia
  • Effective anticoagulation treatment, impossible to suspend
  • Kidney failure (treated by dialysis)
  • Hepatic cirrhosis
  • Patient refusal
  • Patient in custody
  • Patient under guardianship

Outcomes

Primary Outcomes

Mean cost evaluation

Time Frame: 1 month

Mean cost evaluation, for the hospital, of the ambulatory care compared with standard hospitalization for patients who benefit from the ERAS program.

Secondary Outcomes

  • Mean time period required for a postoperative complication care(2 years and 3 months)
  • Quality of life evaluation: EQ-5D (EuroQoL-5 Dimensions) scale(7 and 30 days)
  • Ambulatory care failure rate(2 years and 3 months)
  • Complications rate(30 days)
  • Complications severity classification(30 days)
  • Mean hospital length of stay(2 years and 3 months)
  • Ambulatory colectomies rate(2 years and 3 months)
  • Hospital re-admissions rate(30 days)
  • Rate of complications (Morbidity)(30 days)
  • Rate of death (Mortality)(30 days)
  • Evaluation of complication severity according to Clavien classification(2 years and 3 months)
  • Costs related to postoperative complications(2 years and 3 months)
  • Duty desk call(2 years and 3 months)
  • Mean additional hospital length of stay(2 years and 3 months)
  • Costs related to the management of postoperative complications(2 years and 3 months)

Study Sites (1)

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