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Clinical Trials/NCT03189550
NCT03189550
Completed
Not Applicable

Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality Improvement Project

Vanderbilt University Medical Center1 site in 1 country664 target enrollmentJuly 1, 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Surgery
Sponsor
Vanderbilt University Medical Center
Enrollment
664
Locations
1
Primary Endpoint
Incidence of surgical site infection
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Multimodal perioperative care pathways have evolved into enhanced recovery after surgery (ERAS). ERAS pathways improve the quality of patient care, reduce morbidity, and shorten length of stay. This project will test the hypothesis that implementation of a multi-modal ERAS perioperative care protocol in colorectal surgical patients will result in significantly reduced perioperative morbidity and mortality.

Detailed Description

Multimodal perioperative care pathways have evolved into enhanced recovery after surgery (ERAS). ERAS pathways improve the quality of patient care, reduce morbidity, and shorten length of stay. This large quality improvement project will compare outcomes after standard perioperative practice with those after the implementation of a multi-modal evidence based care pathway, including standardized preoperative preparation, perioperative goal-directed fluid therapy (GFDT), multi-modal perioperative pain management, post operative nausea and vomiting prevention, surgical care and bowel isolation, and surgical site infection prevention. This project will test the hypothesis that implementation of a multi-modal ERAS perioperative care protocol in colorectal surgical patients will result in significantly reduced perioperative morbidity and mortality.

Registry
clinicaltrials.gov
Start Date
July 1, 2014
End Date
February 17, 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Matthew McEvoy

Associate Professor of Anesthesiology

Vanderbilt University Medical Center

Eligibility Criteria

Inclusion Criteria

  • All patients who underwent colorectal surgery at Vanderbilt University Medical Center and whose data is stored in the perioperative data warehouse.

Exclusion Criteria

  • Age \<18 years
  • Weight \<40 kg

Outcomes

Primary Outcomes

Incidence of surgical site infection

Time Frame: Up to 30 days postoperative

Secondary Outcomes

  • Analgesia consumption(Up to 30 days postoperative)
  • Hospital Length of stay (days)(Up to 30 days post operative)
  • Systemic vascular resistance(1 day)
  • Time on ventilator(Up to 30 days postoperative)
  • Post operative anti emetic consumption(Up to 30 days postoperative)
  • Stroke volume(1 day)
  • Post operative pain assessment using 11-point Numeric Pain Rating Scale (NRS)(Up to 30 days postoperative)
  • Occurrence of postoperative complications(Up to 30 days postoperative)
  • Cardiac Index(1 day)
  • Heart rate(1 day)
  • ICU length of stay(Up to 30 days postoperative)

Study Sites (1)

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