To assess the effect of Tranexamic acid in cure of a pigment disorder
Phase 4
- Conditions
- Health Condition 1: null- Melasma
- Registration Number
- CTRI/2018/07/014952
- Lead Sponsor
- Hindu Mission Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with diagnosis of melasma .
2.Age 18 - 55 years, of either gender.
3.Absence of other confounding inflammatory dermatoses (eg. Exogenous ochronosis, Acanthosis nigricans, post inflammatory hyperpigmentation, Pigmented cosmetic dermatitis, Actinic lichen planus, malar rash, etc.)
4.Willing to follow the study procedures and give written informed consent.
Exclusion Criteria
1.Pregnancy and lactation.
2.Any chronic medical illness,
3.History of thrombosis, abnormal bleeding profile,
4.Any medical treatment for melasma within 1 month of entry,
5.Skin resurfacing by dermabrasion, chemical peels, and facial laser within the preceding 9 months,
6.Hypersensitivity to TXA,
7.Abnormal bleeding time, clotting time or platelet count
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MASI ScoreTimepoint: 90 days
- Secondary Outcome Measures
Name Time Method Occurrence of adverse effects. <br/ ><br>Patients satisfaction will be evaluated by a Visual Analogic Scale <br/ ><br>Timepoint: 90 days