A study where we will compare the healing effects of different aqueous-based vehicles used for mixing calcium hydroxide powder and placing it in the root canals during the inter-appointment period while treating patients with pulpal necrosis & symptomatic apical periodontitis.
- Conditions
- Acute apical periodontitis of pulpal origin,
- Registration Number
- CTRI/2023/07/055398
- Lead Sponsor
- Unnati Soma
- Brief Summary
This study aims to investigate the healing outcome of different aqueous-based calcium hydroxide intracanal medicaments in patients with pulpal necrosis and symptomatic apical periodontitis. The primary objective is to evaluate the healing process by comparing pre-treatment and post-treatment observations. A total sample size of 75 patients will be divided into three groups, with each group consisting of 25 patients. The three different aqueous vehicles used for the medicaments are 0.9% saline, 2% chlorhexidine, and 2% lignocaine. The study aims to determine the comparative effectiveness of these aqueous vehicles in promoting healing in the target population. The findings of this research have the potential to contribute valuable insights into the optimal choice of an intracanal medicament for enhancing healing outcomes in patients with pulpal necrosis and symptomatic apical periodontitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 75
Mandibular molar teeth diagnosed with symptomatic apical periodontitis and pulpal necrosis, Teeth with mature apices.
Patients with periodontal disease or systemic disorders, patients taking steroids, pregnant patients, or patients with a history of antibiotic intake in the preceding month, Patients with a history of allergy to any of the components of local anesthesia, chlorhexidine, EDTA, or sodium hypochlorite, Teeth with previous RCT, Severely damaged or mutilated teeth, Patients not willing to participate in the study and did not sign the consent form.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences were expected in apical bone density by comparing the pre-operative PAI scoring & post-operative PAI scoring. Periapical healing at 3months 6 months 9 months & 12 months
- Secondary Outcome Measures
Name Time Method To compare the difference in apical bone density by comparing the pre-operative PAI scoring & post-operative PAI scoring. Periapical healing at 3months 6 months 9 months & 12 months
Trial Locations
- Locations (1)
MANAV RACHNA DENTAL COLLEGE
🇮🇳Faridabad, HARYANA, India
MANAV RACHNA DENTAL COLLEGE🇮🇳Faridabad, HARYANA, IndiaAlpa GuptaPrincipal investigator9050312010alpagupta2008@gmail.com