Cardio-respiratory effects of balancing Positive End Expiratory Pressure with intraabdominal pressures during laparoscopic cholecystectomy
Not Applicable
Completed
- Conditions
- Cardio-respiratory effects (Heart rate, Mean arterial pressure, Cardiac output, Haemoglobin oxygen saturation, End tidal carbon dioxide concentration, Mean and peak airway pressure, Arterial blood gas analysis)Anaesthesiology - Other anaesthesiologyMetabolic and Endocrine - Normal metabolism and endocrine development and function
- Registration Number
- ACTRN12611001264976
- Lead Sponsor
- Dr Yamini Subramani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
All ASA I and II patients between the age group of 15-60 years scheduled to undergo elective laparoscopic cholecystectomy were recruited in the study after obtaining informed consent
Exclusion Criteria
Patients with pre-existing pulmonary disease, cardiovascular disease, neuromuscular disease and pregnant patients were excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean end tidal carbon dioxide concentration. <br>End-tidal carbon dioxide (ETCO2) were recorded using multiparameter monitor (Datex omheda side stream carbon dioxide analyser). Data were analyzed using Graphpad Instat 3.0, Graphpad software, San Diego, CA. Inter-group differences between the variables recorded were analyzed by repeated measures analysis of variance(ANOVA Test) followed by Bonferroni post hoc test of significance.[Preoperatively, 10 min postinduction, 5 min post PEEP, After Capnoperitonium 2 min, 4 min, 6 min, 8 min, 10 min, 15 min, 20 min, 25 min and 30 min.]
- Secondary Outcome Measures
Name Time Method Partial Pressure of arterial oxygenation as assessed using Arterial blood gas analysis[Preoperatively, at 5 minute after PEEP and 30 minute after capnoperitonium];Partial Pressure of arterial carbon dioxide as assessed using Arterial blood gas analysis[Preoperatively, at 5 minute after PEEP and 30 minute after capnoperitonium];Arterial PH as assessed using Arterial blood gas analysis[Preoperatively, at 5 minute after PEEP and 30 minute after capnoperitonium]