A Retrospective Registry of Bleeding, Cardio- and Cerebrovascular Complications in Patients Treated for Head and Neck Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 456
- 主要终点
- decompensated heart failure
研究概览
简要总结
In this retrospective registry trial, the investigators sought to assess the incidence and predictors of cardiovascular and cerebrovascular complications as well as their derivatives (acute coronary syndrome, decompensated heart failure, an episode of atrial fibrillation requiring cardiologist consultation, stroke, pulmonary embolism and venous thromboembolism) in cohort of patients undergoing head and neck surgery.
详细描述
Inclusion criteria consisted of all the consecutive patients (n=456) diagnosed with head and neck cancer at Turku University Hospital between 1999 and 2008. Patients receiving palliative procedures were also included. Patients whose treatment had started in other institute or whose treatment was not finished in the investigators institute and patients with primary diagnosis of skin cancer were excluded from this study. All head and neck surgery operations (n=591) were assessed. Information was collected by the first author of this article from referral letters, patient files, anesthesiology reports, intensive care unit reports, laboratory database, radiology database, electrocardiograms and pathology reports. Death was certificated from national authority for collecting and compiling statistics on various fields of society and economy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed with head and neck cancer in Turku University hospital between 1999-2008
排除标准
- •skin cancer, treatment started in other institute or not finished in our institute
结局指标
主要结局
decompensated heart failure
时间窗: 5 years
myocardial infarction
时间窗: 5 years
new onset atrial fibrillation
时间窗: 5 years
stroke
时间窗: 5 years
bleeding
时间窗: 30 days
all cause mortality
时间窗: 5 years
次要结局
未报告次要终点
研究者
Tuomas Kiviniemi
Cardiologist, MD, PhD
University of Turku
