The Efficacy of Exercise Timing - Effects of Resistance Exercise on Eating Behavior and Energy Metabolism
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Change in PBMCs circadian rhythm genes
研究概览
简要总结
Exercise timing (morning or evening) for optimal weight control is a research topic urgently addressed by scholars in the relevant field. Due to the better control of energy metabolism and physical activity levels in the morning, existing research on resistance exercise and eating behavior primarily focuses on experiments conducted in the morning, with only one study in the afternoon. No research has yet compared the potential differences between morning and evening resistance exercise. A one-year study aims to investigate the impact of morning and evening resistance exercise on physiological metabolism and eating behavior. Eighteen healthy male participants will be randomly assigned to a crossover design study, including AM exercise, PM exercise, and control (rest condition) trials. Variables including subjective appetite, appetite hormones (ghrelin, peptide YY), food preferences, ad libitum eating, dietary records, energy expenditure, and PBMCs circadian rhythm genes will be measured. This preliminary study through a multidimensional observation, the results will contribute to understanding the potential differences and mechanisms of morning and evening resistance exercise on physiological metabolism and eating behavior. In practical applications, conducting resistance exercise in the evening or at night aligns better with current lifestyles. The findings of this study can support the optimization of exercise benefits by validating the choice of exercise timing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age: 20-30
- •weight stable for at least 6 months
排除标准
- •Obesity (BMI > 30 kg/m² or body fat percentage > 25%)
- •Hypertension (blood pressure over 140/90 mmHg)
- •Heart disease
- •Liver or kidney diseases
- •Any other conditions that could potentially influence the study's outcomes
研究组 & 干预措施
The control in all day
Sit and rest in the morning and evening during the day.
The exercise in morning
Resistance exercises are in the following order: squat, bench press, deadlift. Each exercise consists of 3 sets with 7 repetitions, using a load of 70% 1RM with 60 sec of rest between sets.
干预措施: The exercise in morning (Other)
The exercise in evening
Resistance exercises are in the following order: squat, bench press, deadlift. Each exercise consists of 3 sets with 7 repetitions, using a load of 70% 1RM with 60 sec of rest between sets.
干预措施: The exercise in evening (Other)
结局指标
主要结局
Change in PBMCs circadian rhythm genes
时间窗: 3 hours during each study intervention
Circadian rhythm genes in PBMC will be measured, such as Bmal1, Clock, Per1, Per2, Per3, Cry1, Cry2, Cry3, and Tbp in arbitrary units.
Change in lactate
时间窗: 3 hours during each study intervention
lactate in mmol/L
Change in PYY
时间窗: 3 hours during each study intervention
PYY in pg/mL
Change in Leptin
时间窗: 3 hours during each study intervention
Leptin in pg/mL
Subjective appetite Subjective appetite Subjective appetite Subjective appetite Subjective appetite Subjective appetite
时间窗: 3 hours during each study intervention
The appetite perceptions are obtained through a 0-100 mm visual analog scale. The variables assessed include perceptions of hunger (i.e., "How hungry do you feel?"), satisfaction (i.e., "How satisfied do you feel?"), fullness (i.e., "How full do you feel?"), prospective food consumption (i.e., "How much do you think you can eat?"), and nausea (i.e., "How nauseous do you feel?"), with 0 indicating "not at all" and 100 signifying "extremely.".
Change in acyl-Ghrelin
时间窗: 3 hours during each study intervention
acyl-Ghrelin in pg/mL
Energy intake
时间窗: The Before day, the durning day, and the day following the experiment.
Participants will be required to record their diet for the day before, the current day, and the day following the experiment. The energy intake include absolute energy intake and relative energy intake .
Energy expenditure
时间窗: The Before day, the durning day, and the day following the experiment.
Participants will record energy expenditure during resistance exercise, with non-exercise energy expenditure measured using an accelerometer.
次要结局
- change in Cortisol(3 hours during each study intervention)
- Explicit liking(3 hours during each study intervention)
- Explicit wanting(3 hours during each study intervention)
- Taste appeal bias(3 hours during each study intervention)
- Fat appeal bias(3 hours during each study intervention)
- Implicit wanting(3 hours during each study intervention)
- Relative preference(3 hours during each study intervention)
- change in complete blood count(3 hours during each study intervention)
- change in growth hormone(3 hours during each study intervention)