Comparison of platelet rich fibrin, periosteal pedicle graft and subepithelial connective tissue graft in treatment of Millers Class I &/or II gingival recession on multiple adjacent teeth- Randomized controlled trial.
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- to evaluate clinical root coverage, probing depth, clinical attachement level, attached ginigval gain and esthetic outcome obtained all methods.
研究概览
简要总结
Successful coverage of exposed root is necessary for esthetic andfunctional reasons. A variety of surgical techniques have been used to coverrecession type defects. Subepithelialconnective tissue graft (SCTG) is considered gold standard for treatment ofgingival recession1,2,3. Modified coronally advanced flap (MCAF)operation offers a predictable, simple and convenient approach as a root coverage procedure in Miller’s class Iand II recession defects.4 Combining this technique with addition ofplatelet rich fibrin (PRF) improves outcomes like root coverage, amount ofgingival thickness and keratinized tissue width at surgical site5 Periosteum is a highly vascular connective tissue with immenseregenerative potential. It containfibroblasts & their progenitorcells & stem cells. In all age groups, cells of periosteum retain abilityto differentiate into various types of cells. Recent studies have shown that periosteal pedicle graft (PPG) resulted in increased root coverage, width ofattached gingival & keratinized gingiva.2,5
All those treatmentmodalities give good result, with predictability of root coverage, widening of attached and keratinized gingiva.To best of our knowledge, there is no study which compares PRF, PPG and SCTG inthe treatment of gingival recession. Hence, the purpose of this study is to compare clinical outcomesof PRF, PPG and SCTG in treatment of miller’s class I & II gingivalrecession in multiple adjacent teeth.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy participants
- •Millers class I and or II gingival recession on adjacent two to three teeth.
- •Gingival recession depth of atleast one mm
- •Full mouth plaque score less than one.
- •Subjects willing to comply with the study related procedures.
- •Subjects willing to give written consent.
排除标准
- •Medically compromised conditions that contraindicate periodontal surgery.
- •Subjects unable to perform routine oral hygiene procedure or poor patient patient compliance.
- •Pregnant or Lactating females.
- •Mucosal disorders at surgical sites.
结局指标
主要结局
to evaluate clinical root coverage, probing depth, clinical attachement level, attached ginigval gain and esthetic outcome obtained all methods.
时间窗: At baseline, post-operative 3 and 6 months
次要结局
- Patient comfort, complications suah as hematoma, pain, swelling, etc.(during surgery and post- surgical upto 6 months.)