Effect of Duration and Follicle Diameter During Oocyte Pick up on Embryological Parameters

Completed

• Conditions: Embryologic Parameters; Follicle Size; Duration
• Interventions: Procedure: follicle diameter and duration of procedure

• Registration Number: NCT05666401
• Lead Sponsor: Eurofertil IVF Health Center

Brief Summary

Investigators aim to investigate if the time spent for smaller follicles worth to deal with. The difference between follicle groups are recorded for embryological parameters. Results will be analysed for yielding transfer embryo and pregnancy rates between groups.

Detailed Description

There are papers about follicle dimensions and volumes studying their effect on embryologic parameters. But most of these studies are far from practical approach and are not easily applicable, such as 3D volumetric measurement is not feasible for most of the clinics. Also one of the points important for us it to evaluate the duration of the procedure and the possible positive effect of shortening the duration for better results. Investigators plan to measure the follicles just before puncture and arrange two groups. Group 1,follicles with diameter of 17 mm and more, and group 2 follicles between14-17 mm. Maturation, fertilization, cleavage characteristics are recorded. The source of chosen transfer embryo and crio-preserved embryos per cycle is also point of interest.

Study Timeline

• Study Start: 2022-03-19
• Study First Submitted: 2022-12-17
• Study First Submitted QC: 2022-12-17
• Study First Posted: 2022-12-27
• Status Verified: 2024-02
• Primary Completion: 2024-02-17
• Study Completion: 2024-02-17
• Last Update Submitted: 2024-02-17
• Last Update Posted: 2024-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 291

Inclusion Criteria

• 20-40 year old women

Exclusion Criteria

• History of recurrent implantation failure (RIF)
• Known chromosomal abnormality
• Severe male factor and azospermia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group 2	follicle diameter and duration of procedure	follicles with a diameter of 14 mm to 17 mm
group 1	follicle diameter and duration of procedure	follicles with a diameter of 17 mm and more

Primary Outcome Measures

Name	Time	Method
transfer embryo	5 to 7 days	comparing groups as the source of transfer embryo

Secondary Outcome Measures

Name	Time	Method
clinical pregnancy	3 weeks	comparing groups as the source of implanted embryo

Trial Locations

Locations (2)

Bursa Eurofertil IVF center; 🇹🇷 Bursa, Turkey

Eurofertil IVF center; 🇹🇷 Bursa, Turkey