The Factors That Affected the Outcome of Treatment of Congenital Nasolacrimal Duct Obstruction

Completed

• Conditions: Congenital Nasolacrimal Duct Obstruction
• Interventions: Procedure: Probing

• Registration Number: NCT02081781
• Lead Sponsor: Cathay General Hospital

Brief Summary

The purpose of this study was to investigate various potential factors that affected the outcome of treatment of congenital nasolacrimal duct obstruction.

Detailed Description

Congenital nasolacrimal duct obstruction is a common condition during the first few years of childhood. Most cases may resolve spontaneously, but the remaining children whose blockage does not resolve may require primary probing. Controversy remains regarding the optimal timing of the probing procedure. Another controversy is related to the setting of surgery. Therefore, we try to investigate the factors that affected the outcome of treatment of congenital nasolacrimal duct obstruction under the same surgical doctor during the past 13 years in our hospital.

Study Timeline

• Study Start: 2014-02
• Status Verified: 2014-03
• Primary Completion: 2014-03
• Study Completion: 2014-03
• Study First Submitted: 2014-03-05
• Study First Submitted QC: 2014-03-05
• Last Update Submitted: 2014-03-05
• Study First Posted: 2014-03-07
• Last Update Posted: 2014-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• a history of tearing and/or mucopurulent discharge beginning during the first few weeks of life
• anatomical nasolacrimal duct obstruction

Exclusion Criteria

• previous probing
• glaucoma
• trauma
• lid malpositions
• craniofacial anomalies
• congenital mucocele of the nasolacrimal sac

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Probing, topical anesthesia	Probing	Nasolacrimal duct obstruction (NLDO) is a quite common condition among the infants. An imperforate membrane at the distal end of the nasolacrimal duct is the main cause of occlusion. Children with the signs of NLDO presenting with epiphora and/or mucous discharge were included in this study. Intervention with probing under topical anesthesia was performed on the same surgeon. And success rate was evaluated.

Primary Outcome Measures

Name	Time	Method
probing success: both anatomical patency of the duct and functional free of symptoms	one week

Trial Locations

Locations (1)

Department of Ophthalmology, Cathay General Hospital; 🇨🇳 Taipei, Taiwan