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Clinical Trials/NCT03509311
NCT03509311
Completed
Not Applicable

Investigation of Physical Activity Level, Cardiorespiratory Fitness and Quality of Life in Patients With Asthma

Gazi University1 site in 1 country72 target enrollmentApril 20, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Asthma
Sponsor
Gazi University
Enrollment
72
Locations
1
Primary Endpoint
Physical Activity Level
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The primary aim of the study is to evaluate the physical activity level in patients with asthma. The secondary aims of the study are assesment of maximal and functional exercise capacity, respiratory functions, respiratory muscle strength and endurance, peripheral muscle strength, depression and anxiety levels, disease specific and respiratory quality of life, sleep and coughing associated quality of life, asthma self-management knowledge level and fatigue severity in patients with asthma.

Detailed Description

Asthma is an obstructive pulmonary disease and thus it affects respiratory functions. Dyspnea, fatigue and bronchial hyperreactivity symptoms are commonly seen on patients with asthma. It is known that physical activity level of asthmatic patients is reduced. Few researches have investigated asthmatic patients' physical activity level and these researches mainly focused on self reported physical activity level. How differing maximal and submaximal exercise capacity of asthmatic patients is not well known. Because previous researches compared only different severity levels of the disease. It is reported that peripheral muscle strength of asthmatic patients is lower than healthy individuals' peripheral muscle strength. But evidences about this subject are insufficient. Asthmatic patients' respiratory muscle strength is lower than healthy individuals' respiratory muscle strength. But it is not clear if endurance is lower as respiratory muscle strength too, or not. It is reported that quality of life of asthmatic patients is worst than healthy individuals'. According to the sample size analysis 36 patients and 36 healthy individuals with similar demographic characteristics will be included the study. Patients and healthy individuals will be selected according to predetermined inclusion and exclusion criteria. The assessments will be completed in two days. Maximal exercise capacity will be assessed using cardiopulmonary exercise testing (CPET), functional exercise capacity using six minute stepper test, physical activity using multi-sensor activity monitor, pulmonary function using spirometry, respiratory muscle strength using mouth pressure device, peripheral muscle strength using hand held dynamometer, respiratory muscle endurance using incremental threshold loading test, depression using Beck Depression Inventory (Turkish version), anxiety using Beck Anxiety Inventory (Turkish version), disease specific quality of life using Asthma Quality of Life Questionnaire (Turkish version) and St. George Respiratory Questionnaire (Turkish version), cough related quality of life using Leicester Cough Questionnaire (Turkish version), sleep related quality of life using Pittsburgh Sleep Quality Index (Turkish version), asthma control level using Asthma Control Test (Turkish version), disease management knowledge level using Asthma Self-Management Questionnaire (Turkish version).

Registry
clinicaltrials.gov
Start Date
April 20, 2018
End Date
July 30, 2019
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Meral Boşnak Güçlü

Assoc. Prof.

Gazi University

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Physical Activity Level

Time Frame: First Day

Multi sensor activity monitor

Secondary Outcomes

  • Pulmonary Functions(First Day)
  • Peripheral Muscle Strength(First Day)
  • Fatigue Severity(First Day)
  • Respiratory Muscle Strength(First Day)
  • Respiratory Muscle Endurance(First day)
  • Disease Spesific Quality of Life(First Day)
  • Asthma Self-Management Knowledge(First Day)
  • Functional Exercise Capacity(First Day)
  • Maximal Exercise Capacity(Second Day)
  • Anxiety(Second Day)
  • Respiratory Associated Quality of Life (respiratory)(Second day)
  • Sleep Quality(Second day)
  • Depression(Second day)
  • Cough Related Quality of Life(Second day)

Study Sites (1)

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