Amniotic membrane extract drops in wound healing of semi-thickness skin donor site
Phase 2
Recruiting
- Conditions
- Wound.Open wound of unspecified body region
- Registration Number
- IRCT201703148177N16
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
age 18-65 years old; requiring skin graft surgery; signing informed consent. Exclusion criteria: removal of skin graft from the outside of the thigh; conditions and diseases in which the immune system is weakened and wound healing is delayed such as: diabetes, cancer, immune system dysfunction, drugs that suppress the immune system, taking corticosteroids, smoking and alcohol; patients who do not cooperate with treatment and referrals necessary after surgery.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wound Healing. Timepoint: Observation, examination and photography on days 1 and 12 after surgery and during spontaneous separation of Vaseline gauze from wound. Method of measurement: Observation, examination and photography.
- Secondary Outcome Measures
Name Time Method Cost. Timepoint: The end of the study. Method of measurement: Cost estimation of the number of drops used in each treatment group.;Scar. Timepoint: 6 months after surgery. Method of measurement: Vancouver Scar Scale, Patient and Observer Scar Assessment Scale (POSAS).;Infection. Timepoint: Every 3 days after surgery until complete wound healing. Method of measurement: Observation, examination and wound culture.;Pain. Timepoint: 3, 6 and 12 days after surgery. Method of measurement: Visual Analogue Scale (VAS).